GARETH Anscombe is waiting on a scan on his injured right knee after limping out of Wales’ World Cup warm-up defeat to England, writes Chris Kirwan.

The fly-half, who has overtaken Dan Biggar to be the Grand Slam champions’ starter, was helped from the field after 33 minutes of the 33-19 defeat at Twickenham.

He will have a scan on Monday as will scrum-half Tomos Williams, who was named in the matchday squad to face England only to pull out after a blow to his shoulder in training.

Of prime concern is Ospreys playmaker Anscombe, with Warren Gatland naming his final 31 for Japan on Sunday, September 1.

"I’ve spoken to the physios, he’s got to get a scan,” said the head coach. “If it’s just a strain of the ligaments then he’ll be out for a few weeks, but we’ll know more details after the scan.”

Anscombe was struggling with the injury before leaving the field.

“The message was to see how it goes. He didn't do any further damage to the knee by playing on, it was already done,” said Gatland. "Players see if they can run off a knock, he wasn't able to do that."

The Six Nations champions were unable to extend their 14-Test winning streak despite tries by scrum-half Gareth Davies, wing George North and replacement prop Wyn Jones at Twickenham.

They shipped three tries and were always chasing the game after making a sluggish start.

Gatland is confident that Wales will respond with victory when they entertain England at Principality Stadium on Saturday.

“Any loss is disappointing but it’s not competition phase,” said Gatland. “We will be a lot better next week.”